Anti-Inflammatory Effect of Simvastatin in Hemodialysis Patients

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Anti-Inflammatory Effect of Simvastatin in Hemodialysis Patients

BACKGROUND Patients in the final stages of renal failure have accelerated inflammation conditions. Inflammation causes progressive kidney damage, faster progression of atherogenesis, chronic malnutrition and increased anemia, resulting in lower life expectancy of patients under dialysis. Statins have pleiotropic effects, because the drug has effects more than just decreasing lipids such as anti...

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anti-inflammatory effect of simvastatin in hemodialysis patients

conclusions end stage renal disease (esrd) have accelerated inflammatory conditions. simvastatin clearly lowers the serum levels of crp and il-6, and the white blood cell count in dialysis patients. administering simvastatin to dialysis patients is safe. results at baseline, each of treatment and control groups had similar characteristics. during the study, the average level of crp decreased in...

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Anti-inflammatory effects of simvastatin in nonsteroidal anti-inflammatory drugs-induced small bowel injury.

Small bowel injury can occur as the result of a multifaceted process that includes increased acid secretion, generation of reactive oxygen species, and cyclooxygenase inhibition. However, no effective medication for small bowel ulceration is available. Simvastatin is an important lipid-lowering agent with anti-inflammatory activity. We aimed to validate the effects of simvastatin in vitro and i...

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Anti-inflammatory effects of Simvastatin in patients with acute intracerebral hemorrhage in an intensive care unit

Intracerebral hemorrhage is one of the most common types of cerebrovascular disease in humans and often causes paralysis, a vegetative state and even death. Patients with acute intracerebral hemorrhage are frequently monitored in intensive care units (ICUs). Spontaneous intracerebral hemorrhage is associated with a higher rate of mortality and morbidity than other intracephalic diseases. The ex...

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Anti-Inflammatory Effect of Taurine in Burned Patients.

PURPOSE Burn induced inflammatory response can be mediated by reactive oxygen metabolites and accompanied by multiple organ dysfunction. Taurine has protective effects against various inflammatory conditions. The aim of this study was to determine the effect of Taurine supplement in thermal burn victims. METHODS Thirty patients with severe thermal burns were enrolled in this randomized double...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Natural Pharmaceutical Products

سال: 2015

ISSN: 1735-7780,2228-7876

DOI: 10.17795/jjnpp-17962